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Adviser Profile

As of Date 03/26/2024
Adviser Type - Large advisory firm
Number of Employees 4 33.33%
of those in investment advisory functions 3
Registration SEC, Approved, 10/29/2013
AUM* 432,480,569 2.49%
of that, discretionary 432,480,569 2.49%
Private Fund GAV* 421,822,670 4.11%
Avg Account Size 216,240,285 2.49%
SMA’s Yes
Private Funds 1
Contact Info 617 xxxxxxx

Client Types

- Pooled investment vehicles
- Other investment advisers

Advisory Activities

- Portfolio management for pooled investment vehicles
- Portfolio management for businesses

Compensation Arrangments

- A percentage of assets under your management
- Performance-based fees

Recent News

Reported AUM

Discretionary
Non-discretionary
833M 714M 595M 476M 357M 238M 119M
2015 2016 2017 2018 2019 2020 2021 2022 2023

Private Funds



Employees

Private Funds Structure

Fund Type Count GAV
Fund TypeHedge Fund Count1 GAV$421,822,670

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Top Holdings

Stock Ticker Stock Name $ Position % Position $ Change # Change
Stck Ticker415858109 Stock NameHARROW HEALTH INC $ Position$83,351,100 % Position19.00% $ Change61.00% # Change2.00%
Stck Ticker88322Q108 Stock NameTG THERAPEUTICS INC $ Position$40,561,200 % Position9.00% $ Change17.00% # Change0.00%
Stck Ticker67576A100 Stock NameOCULAR THERAPEUTIX INC $ Position$36,303,300 % Position8.00% $ Change-40.00% # Change-20.00%
Stck Ticker76243J105 Stock NameRHYTHM PHARMACEUTICALS INC $ Position$21,145,900 % Position5.00% $ Change-5.00% # Change0.00%
Stck Ticker492327101 Stock NameKEROS THERAPEUTICS INC $ Position$16,794,750 % Position4.00% $ Change-31.00% # Change0.00%
Stck Ticker45257U108 Stock NameIMMUNOME INC $ Position$13,340,250 % Position3.00% $ Change # Change
Stck Ticker04335A105 Stock NameARVINAS INC $ Position$14,774,100 % Position3.00% $ Change8.00% # Change68.00%
Stck Ticker03828A101 Stock NameAPPLIED THERAPEUTICS INC' $ Position$7,845,600 % Position2.00% $ Change114.00% # Change-5.00%
Stck Ticker35104E100 Stock Name4D MOLECULAR THERAPEUTICS INC $ Position$7,257,293 % Position2.00% $ Change-34.00% # Change0.00%
Stck Ticker00445A100 Stock NameACELYRIN INC $ Position$6,967,800 % Position2.00% $ Change-35.00% # Change0.00%

Brochure Summary

Overview

Firm Description and History Opaleye Management Inc. is a Massachusetts corporation formerly named Risk/Reward Capital Management Corporation formed in 1996. Risk/Reward Capital Management Corporation changed the name to Opaleye Management Inc. in 2014. James Silverman is the sole owner. Business Summary Opaleye provides discretionary investment management services to Opaleye, L.P., a Delaware limited partnership (hereafter the “Fund”). Opaleye GP LLC, a Delaware limited liability company, is the general partner (the “General Partner”) to the Fund. Opaleye is related to the Fund’s General Partner by virtue of common ownership and control. Opaleye manages the Fund on a discretionary basis in accordance with the terms and conditions of the Fund's confidential private placement memorandum and its limited partnership agreement (collectively, the “Offering Documents”). We do not tailor the Fund’s management to the particular needs of any investor in the Fund. The Fund generally invests in equity securities of U.S. and foreign small and mid-cap biotechnology and specialty pharmaceutical and device companies, which may include private companies. Typically, these companies are developing therapies and treatments intended for humans. Interests in the Fund are offered in
reliance upon various exemptions available under the securities laws for transactions in securities not involving a public offering. Investors in the Fund should be aware of additional risks, restrictions on withdrawals and redemptions, and other important information associated with an investment in the Fund. This information is outlined in the Fund's Offering Documents. Accordingly, prospective investors should refer to the Offering Documents for information regarding these important additional considerations and risks. In addition, Opaleye also serves as a portfolio manager and provides discretionary investment management services for a separately managed account (the “Managed Account”). The Managed Account is a parallel managed account that pursues a similar investment objective and strategy and invests side-by-side in most of the same positions as the Fund. We managed the Managed Account as outlined in the management account agreement between Opaleye and the Managed Account client. We do not tailor the Managed Account’s management to the particular needs of the Managed Account client. Client Assets Under Management Discretionary assets under our firm’s management were approximately 432,500,000 as of December 31, 2023. We do not currently manage any non-discretionary assets.